Article
HLA-C expression levels define permissible mismatches in hematopoietic cell transplantation.
Blood - 18 Dec 2014
Petersdorf Effie W, Gooley Theodore A, Malkki Mari, Bacigalupo Andrea P, Cesbron Anne, Du Toit Ernette, Ehninger Gerhard, Egeland Torstein, Fischer Gottfried F, Gervais Thibaut, Haagenson Michael D, Horowitz Mary M, Hsu Katharine, Jindra Pavel, Madrigal Alejandro, Oudshoorn Machteld, Ringdén Olle, Schroeder Marlis L, Spellman Stephen R, Tiercy Jean-Marie, Velardi Andrea, Witt Campbell S, O'Huigin Colm, Apps Richard, Carrington Mary
Abstract excerpt
Life-threatening graft-versus-host disease (GVHD) limits the use of HLA-C-mismatched unrelated donors in transplantation. Clinicians lack criteria for donor selection when HLA-C-mismatched donors are a patient's only option for cure. We examined the role for HLA-C expression levels to identify pe...
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