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Article

Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency.

The European respiratory journal - 1 Feb 2015

Van't Wout Emily F A, van Schadewijk Annemarie, Lomas David A, Stolk Jan, Marciniak Stefan J, Hiemstra Pieter S

Abstract excerpt

α1-antitrypsin deficiency is the most widely recognised genetic disorder causing chronic obstructive pulmonary disease (COPD). Mutant Z α1-antitrypsin expression has previously been linked to intracellular accumulation and polymerisation of this proteinase inhibitor. Subsequently, this has been d...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25323228
DOI: 10.1183/09031936.00046114

Genes

XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25323228-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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