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Article

Association of TNFSF8 regulatory variants with excessive inflammatory responses but not leprosy per se.

The Journal of infectious diseases - 15 Mar 2015

Fava Vinicius M, Cobat Aurélie, Van Thuc Nguyen, Latini Ana Carla P, Stefani Mariane M A, Belone Andrea F, Ba Nguyen Ngoc, Orlova Marianna, Manry Jérémy, Mira Marcelo T, Thai Vu Hong, Abel Laurent, Alcaïs Alexandre, Schurr Erwin

Abstract excerpt

BACKGROUND: Type 1 reactions (T1R) affect a considerable proportion of patients with leprosy. In those with T1R, the host immune response pathologically overcompensates for the actual infectious threat, resulting in nerve damage and permanent disability. Based on the results of a genome-wide asso...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25320285
DOI: 10.1093/infdis/jiu566

Genes

TNFSF15
TNFSF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25320285-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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