Article
Investigating genome reduction of Bordetella pertussis using a multiplex PCR-based reverse line blot assay (mPCR/RLB).
BMC research notes - 15 Oct 2014
Lam Connie, Octavia Sophie, Sintchenko Vitali, Gilbert Gwendolyn L, Lan Ruiting
Abstract excerpt
BACKGROUND: The genetic composition of the bacterium causing whooping cough, Bordetella pertussis, has been investigated using microarray studies in order to examine potential genetic contributors to the disease re-emergence in the past decade. Regions of difference (RDs) have been previously identified as clusters of genes flanked by insertion sequences which are variably present in different sets of isolates,...
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