Article
Temporal analysis of French Bordetella pertussis isolates by comparative whole-genome hybridization.
Microbes and infection - 1 Jul 2006
Caro Valérie, Hot David, Guigon Ghislaine, Hubans Christine, Arrivé Mathilde, Soubigou Guillaume, Renauld-Mongénie Geneviève, Antoine Rudy, Locht Camille, Lemoine Yves, Guiso Nicole
Abstract excerpt
Bordetella pertussis, a gram-negative beta-proteobacterium, is the agent of whooping cough in humans. Whooping cough remains a public health problem worldwide, despite well-implemented infant/child vaccination programs. It continues to be endemic and is observed cyclically in vaccinated populations. Classical molecular subtyping methods indicate that genome diversity among B. pertussis isolates is limited....
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