Article
Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli.
Bioinformatics (Oxford, England) - 1 Feb 2015
Vlasblom James, Zuberi Khalid, Rodriguez Harold, Arnold Roland, Gagarinova Alla, Deineko Viktor, Kumar Ashwani, Leung Elisa, Rizzolo Kamran, Samanfar Bahram, Chang Luke, Phanse Sadhna, Golshani Ashkan, Greenblatt Jack F, Houry Walid A, Emili Andrew, Morris Quaid, Bader Gary, Babu Mohan
Abstract excerpt
MOTIVATION: The model bacterium Escherichia coli is among the best studied prokaryotes, yet nearly half of its proteins are still of unknown biological function. This is despite a wealth of available large-scale physical and genetic interaction data. To address this, we extended the GeneMANIA function prediction web application developed for model eukaryotes to support E.coli. RESULTS: We integrated 48 distinct...
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