An integrative, multi-scale, genome-wide model reveals the phenotypic landscape of Escherichia coli.

Abstract excerpt

Given the vast behavioral repertoire and biological complexity of even the simplest organisms, accurately predicting phenotypes in novel environments and unveiling their biological organization is a challenging endeavor. Here, we present an integrative modeling methodology that unifies under a common framework the various biological processes and their interactions across multiple layers. We trained this...

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