Article
Rapid key gene discovery for bacterial shape: a cross-species machine learning approach.
BMC microbiology - 3 Nov 2025
Liu Qi, Liu Haida, Shi Jianqiang, Xu Chuangchuang, Xie Yanghe, Hu Shunli, Zhang Yunhua, Han Guomin
Abstract excerpt
Accurately identifying genes responsible for specific functions is a cornerstone of biological research, but current methods are often limited to single-species analyses. Here, we present a novel method, called Genomic and Phenotype-based machine learning for Gene Identification (GPGI), that leverages large-scale, cross-species genomic and phenotypic data for functional gene discovery. Using bacterial rod-shape...
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