Article
Proteome Data Improves Protein Function Prediction in the Interactome of Helicobacter pylori.
Molecular & cellular proteomics : MCP - 1 May 2018
Wuchty Stefan, Müller Stefan A, Caufield J Harry, Häuser Roman, Aloy Patrick, Kalkhof Stefan, Uetz Peter
Abstract excerpt
Helicobacter pylori is a common pathogen that is estimated to infect half of the human population, causing several diseases such as duodenal ulcer. Despite one of the first pathogens to be sequenced, its proteome remains poorly characterized as about one-third of its proteins have no functional annotation. Here, we integrate and analyze known protein interactions with proteomic and genomic data from different...
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