Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common genetic variants in NEFL influence gene expression and neuroblastoma risk.

Cancer research - 1 Dec 2014

Capasso Mario, Diskin Sharon, Cimmino Flora, Acierno Giovanni, Totaro Francesca, Petrosino Giuseppe, Pezone Lucia, Diamond Maura, McDaniel Lee, Hakonarson Hakon, Iolascon Achille, Devoto Marcella, Maris John M

Abstract excerpt

The genetic etiology of sporadic neuroblastoma is still largely obscure. In a genome-wide association study, we identified single-nucleotide polymorphisms (SNP) associated with neuroblastoma at the CASC15, BARD1, LMO1, DUSP12, HSD17B12, HACE1, and LIN28B gene loci, but these explain only a small fraction of neuroblastoma heritability. Other neuroblastoma susceptibility genes are likely hidden among signals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genome-Wide Association Study

Share to HEK293 Cells

Share to Neuroblastoma

Share to Neurofilament Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25312269
DOI: 10.1158/0008-5472.CAN-14-0431
PMCID: PMC4253722

Genes

NEFL
BARD1
DUSP12
LMO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common genetic variants in NEFL influence gene expression and neuroblastoma risk.PMID 25312269Read ↗

Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.Semantic proximity Read ↗

Phenotype restricted genome-wide association study using a gene-centric approach identifies three low-risk neuroblastoma susceptibility Loci.Semantic proximity Read ↗

Integrative genomic analyses identify neuroblastoma risk genes involved in neuronal differentiation.Semantic proximity Read ↗

A genome-wide association study in Chinese children identifies and functionally validates 5q31.1 as a neuroblastoma susceptibility locusSemantic proximity Read ↗

Recent insights into the biology of neuroblastomaSemantic proximity Read ↗

The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation.Semantic proximity Read ↗

Research progress of neuroblastoma related gene variations.Semantic proximity Read ↗

Genetics and genomics of neuroblastoma.Semantic proximity Read ↗

Integrative genomics identifies LMO1 as a neuroblastoma oncogene.Semantic proximity Read ↗

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus.Semantic proximity Read ↗

Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.Semantic proximity Read ↗

CFDP1 is a neuroblastoma susceptibility gene that regulates transcription factors of the noradrenergic cell identity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.