Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New insights in AML biology from genomic analysis.

Seminars in hematology - 1 Oct 2014

Perry Ashley M, Attar Eyal C

Abstract excerpt

Advancements in sequencing techniques have led to the discovery of numerous genes not previously implicated in acute myeloid leukemia (AML) biology. Further in vivo studies are necessary to discern the biological impact of these mutations. Murine models, the most commonly used in vivo system, provide a physiologic context for the study of specific genes. These systems have provided deep insights into the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Cytogenetic Analysis
Share to ASXL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNMT3A gene

Share to Genomics

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Nucleophosmin

Source

Identifiers

PMID: 25311741
DOI: 10.1053/j.seminhematol.2014.08.005

Genes

ASXL1
DNMT3A
EED
IDH1
NPM1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New insights in AML biology from genomic analysis.PMID 25311741Read ↗

Acute myeloid leukaemia genomics.Semantic proximity Read ↗

Genomics of Acute Myeloid Leukemia Diagnosis and Pathways.Semantic proximity Read ↗

Molecular pathogenesis of AML: translating insights to the clinic.Semantic proximity Read ↗

A concise review on the molecular genetics of acute myeloid leukemia.Semantic proximity Read ↗

Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia.Semantic proximity Read ↗

The Epigenetic Landscape of Acute Myeloid LeukemiaSemantic proximity Read ↗

Molecular Mutations and Their Cooccurrences in Cytogenetically Normal Acute Myeloid LeukemiaSemantic proximity Read ↗

Current findings for recurring mutations in acute myeloid leukemia.Semantic proximity Read ↗

The genomic and epigenomic landscapes of AML.Semantic proximity Read ↗

Descriptive and Functional Genomics in Acute Myeloid Leukemia (AML): Paving the Road for a CureSemantic proximity Read ↗

The molecular basis of myeloid malignancies.Semantic proximity Read ↗

Translating recent advances in the pathogenesis of acute myeloid leukemia to the clinic.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.