Article
The S100A4 D10V polymorphism is related to cell migration ability but not drug resistance in gastric cancer cells.
Oncology reports - 1 Dec 2014
Yuan Tein-Ming, Liang Ruei-Yue, Hsiao Nai-Wan, Chuang Show-Mei
Abstract excerpt
Upregulation of the metastasis-promoting S100A4 protein has been linked to tumor migration and invasion, and clinical studies have demonstrated that significant expression of S100A4 in primary tumors is indicative of poor prognosis. However, the involvement of S100A4 in the drug responsiveness of gastric cancer remains unclear. In the present study, we used gastric cancer cell lines as a model to investigate the...
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