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Article

The C-terminal region of S100A4 is important for its metastasis-inducing properties.

Oncogene - 23 Jun 2005

Zhang Shu, Wang Guozheng, Liu Dong, Bao Zhengzheng, Fernig David G, Rudland Philip S, Barraclough Roger

Abstract excerpt

The EF-hand protein, S100A4, binds calcium ions and interacts specifically in vitro with protein targets. Elevated levels of S100A4 have been shown to produce a metastatic phenotype in independent models of breast cancer. The presence of S100A4 in the carcinoma cells of patients with different carcinomas is associated with reduced patient survival. In order to identify the region of the S100A4 molecule that is...

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PMID: 15856021
DOI: 10.1038/sj.onc.1208663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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