Article
Downregulation of 425G>a variant of calcium-binding protein S100A14 associated with poor differentiation and prognosis in gastric cancer.
Journal of cancer research and clinical oncology - 1 Apr 2015
Zhang Qingying, Zhu Min, Cheng Wenxiang, Xing Rui, Li Wenmei, Zhao Min, Xu Liyan, Li Enmin, Luo Guangbin, Lu Youyong
Abstract excerpt
PURPOSE: Altered level of S100 calcium-binding proteins is involved in tumor development and progression. However, their role in gastric cancer (GC) is not well documented. We investigated the expression pattern of S100 proteins and differentiation or prognosis as well as possible mechanisms in GC. METHODS: RT-PCR, Western blot analysis, and immunohistochemistry were used to determine the mRNA and protein...
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