Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic factors associated with naevus count and dermoscopic patterns: preliminary results from the Study of Nevi in Children (SONIC).

The British journal of dermatology - 1 Apr 2015

Orlow I, Satagopan J M, Berwick M, Enriquez H L, White K A M, Cheung K, Dusza S W, Oliveria S A, Marchetti M A, Scope A, Marghoob A A, Halpern A C

Abstract excerpt

BACKGROUND: Melanocytic naevi are an important risk factor for melanoma. Naevi with distinct dermoscopic patterns can differ in size, distribution and host pigmentation characteristics. OBJECTIVES: We examined MC1R and 85 other candidate loci in a cohort of children to test the hypothesis that the development and dermoscopic type of naevi are modulated by genetic variants. METHODS: Buccal DNAs were obtained from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinase 6
Share to Group VI Phospholipases A2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferon Regulatory Factors

Share to Nevus, Pigmented

Share to Poly (ADP-Ribose) Polymerase-1

Share to Poly(ADP-ribose) Polymerases

Share to Receptor, Melanocortin, Type 1

Share to Sunlight

Source

Open in PubMed Open full text

Identifiers

PMID: 25307738
DOI: 10.1111/bjd.13467
PMCID: PMC4382400

Genes

PARP1
CDK6
CDKN1B
MC1R
MTAP
PLA2G6
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic factors associated with naevus count and dermoscopic patterns: preliminary results from the Study of Nevi in Children (SONIC).PMID 25307738Read ↗

Influence of germline genetic variants on dermoscopic features of melanoma.Semantic proximity Read ↗

Genome-Wide Association Study of Nevus Count Reveals Opposing Effects of Genetic Loci Near IRF4 and MC1R on Flat Versus Raised Nevus Count in the Brisbane Twin Nevus Study: A Cross-Sectional Analysis.Semantic proximity Read ↗

Dermoscopic features of melanocytic skin lesions in Greek children and adolescents and their association with environmental factors and skin types.Semantic proximity Read ↗

Association between genetic factors, naevus count and dermoscopic pattern.Semantic proximity Read ↗

IRF4 variants have age-specific effects on nevus count and predispose to melanoma.Semantic proximity Read ↗

Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma.Semantic proximity Read ↗

A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.Semantic proximity Read ↗

The genomic landscape of childhood and adolescent melanoma.Semantic proximity Read ↗

Polymorphisms in nevus-associated genes MTAP, PLA2G6, and IRF4 and the risk of invasive cutaneous melanoma.Semantic proximity Read ↗

The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive mitogen-activated protein kinase pathway activation.Semantic proximity Read ↗

UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents.Semantic proximity Read ↗

Body site‐specific genetic effects influence naevus count distribution in womenSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.