Article
Epigenome-wide association study for Parkinson's disease.
Neuromolecular medicine - 1 Dec 2014
Moore Kerry, McKnight Amy Jayne, Craig David, O'Neill Francis
Abstract excerpt
A methylation-based EWAS on carefully phenotyped individuals with Parkinson's disease (PD) was conducted to reveal prioritised genes and pathways with statistically significant and sizable changes in PD and in the anxiety that often accompanies it. This was followed by subsequent replication of top-ranked CpG sites. Using the Infinium(®) HumanMethylation 450K beadchip (Illumina Inc., USA), twenty unique genes...
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