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Article

The codon 399 Arg/Gln XRCC1 polymorphism is associated with lung cancer in Indians.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Natukula Kirmani, Jamil Kaiser, Pingali Usha Rani, Attili Venkata Satya Suresh, Madireddy Umamaheshwar Rao Naidu

Abstract excerpt

BACKGROUND: The XRCC1 (X-ray repair cross complimenting group-I) gene in BER (base excision repair) pathway is essential for DNA repair process. Polymorphisms in this gene are associated with variations in the repair efficiency which might predispose individuals to development of various cancers. Two variants of XRCC1gene (at codon 399), Gln/Gln and Arg/Gln, have been shown to be related to lowered DNA repair...

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Identifiers

PMID: 24175813
DOI: 10.7314/apjcp.2013.14.9.5275

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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