Article
Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of northern Spain.
BMC cancer - 16 Aug 2007
López-Cima M Felicitas, González-Arriaga Patricia, García-Castro Laura, Pascual Teresa, Marrón Manuel G, Puente Xose S, Tardón Adonina
Abstract excerpt
BACKGROUND: Polymorphisms in DNA repair genes have been associated to repair DNA lesions, and might contribute to the individual susceptibility to develop different types of cancer. Nucleotide excision repair (NER), base excision repair (BER), and double-strand break repair (DSBR) are the main DNA repair pathways. We investigated the relationship between polymorphisms in two NER genes, XPC (poly (AT)...
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