Article
Higher order genes interaction in DNA repair and cytokine genes polymorphism and risk to lung cancer in North Indians.
Journal of cancer research and therapeutics - 1 Jan 2000
Ritambhara, Kumar Rishabh, Gupta Maneesh Kumar, Gautam Priyanka, Tiwari Sonia, Vijayraghavalu Sivakumar, Shukla Girish C, Kumar Munish
Abstract excerpt
Context: Lung cancer pathological process involves cumulative effects exerted by gene polymorphism(s), epigenetic modifications, and alterations in DNA repair machinery. Further, DNA damage due to oxidative stress, chronic inflammation, and the interplay between genetic and environmental factors is also an etiologic milieu of this malignant disease. Aims: The present study aims to assess the prognostic value of...
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