Article
Complexin2 modulates working memory-related neural activity in patients with schizophrenia.
European archives of psychiatry and clinical neuroscience - 1 Mar 2015
Hass Johanna, Walton Esther, Kirsten Holger, Turner Jessica, Wolthusen Rick, Roessner Veit, Sponheim Scott R, Holt Daphne, Gollub Randy, Calhoun Vince D, Ehrlich Stefan
Abstract excerpt
The specific contribution of risk or candidate gene variants to the complex phenotype of schizophrenia is largely unknown. Studying the effects of such variants on brain function can provide insight into disease-associated mechanisms on a neural systems level. Previous studies found common variants in the complexin2 (CPLX2) gene to be highly associated with cognitive dysfunction in schizophrenia patients....
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