Article
Genomic determinants of triglyceride and cholesterol distribution into lipoprotein fractions in the rat.
PloS one - 1 Jan 2014
Hodúlová Miloslava, Šedová Lucie, Křenová Drahomíra, Liška František, Krupková Michaela, Kazdová Ludmila, Tremblay Johanne, Hamet Pavel, Křen Vladimír, Šeda Ondřej
Abstract excerpt
The plasma profile of major lipoprotein classes and its subdivision into particular fractions plays a crucial role in the pathogenesis of atherosclerosis and is a major predictor of coronary artery disease. Our aim was to identify genomic determinants of triglyceride and cholesterol distribution into lipoprotein fractions and lipoprotein particle sizes in the recombinant inbred rat set PXO, in which alleles of...
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