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Article

HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles.

Folia biologica - 1 Jan 1999

Pravenec M, Kren V, Krenová D, Bíla V, Zídek V, Simáková M, Musilová A, van Lith H A, van Zutphen L F

Abstract excerpt

The HXB/Ipcv and BXH/Cub sets of recombinant inbred (RI) strains were derived from the spontaneously hypertensive rats (SHR/OlaIpcv) and normotensive Brown Norway (BN-Lx/Cub) rats. The RI strains were produced as a model system for genetic and correlation analysis of spontaneous hypertension and other risk factors of cardiovascular disease such as insulin resistance and dyslipidemia. The RI strains were...

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PMID: 10730889

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