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Article

HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles.

Folia biologica - 1 Jan 1999

Pravenec M, Kren V, Krenová D, Bíla V, Zídek V, Simáková M, Musilová A, van Lith H A, van Zutphen L F

Abstract excerpt

The HXB/Ipcv and BXH/Cub sets of recombinant inbred (RI) strains were derived from the spontaneously hypertensive rats (SHR/OlaIpcv) and normotensive Brown Norway (BN-Lx/Cub) rats. The RI strains were produced as a model system for genetic and correlation analysis of spontaneous hypertension and other risk factors of cardiovascular disease such as insulin resistance and dyslipidemia. The RI strains were...

Topics

Alleles
Animals
Cardiovascular Diseases
Genetic Markers
Genetic Predisposition to Disease
Rats
Rats, Inbred BN
Rats, Inbred SHR
Rats, Inbred Strains
Recombination, Genetic
Risk Factors

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PMID: 10730889

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