Article
Metabolic characterization of insulin resistance syndrome feature loci in three brown Norway-derived congenic strains.
Folia biologica - 1 Jan 2002
Seda O, Sedová L, Kazdová L, Krenová D, Kren V
Abstract excerpt
Studies on genetic determination of the insulin resistance syndrome in rat models revealed several susceptibility loci for features of this complex phenotype, i.e. dyslipidemia, insulin resistance and obesity. We analysed the influence of introgression of the RNO4, RNO20 segments of SHR origin and RNO8 segment of PD/Cub origin (all previously shown to be involved in (dys)regulation of carbohydrate and lipid...
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