Article
T-cell levels are prognostic in mantle cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2014
Nygren Lina, Wasik Agata M, Baumgartner-Wennerholm Stefanie, Jeppsson-Ahlberg Åsa, Klimkowska Monika, Andersson Patrik, Buhrkuhl Daren, Christensson Birger, Kimby Eva, Wahlin Björn E, Sander Birgitta
Abstract excerpt
PURPOSE: The purpose of this study was to investigate the impact of T-cell subsets on pathologic and clinical features including disease outcome in mantle cell lymphoma (MCL). EXPERIMENTAL DESIGN: Cell populations were investigated using flow cytometry in diagnostic MCL (n = 153) and reactive (n = 26) lymph node biopsies. Levels of tumor cells, T cells, T-cell subsets, and the CD4:CD8 ratio were assessed and...
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