Article
A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease.
Blood - 15 Jun 2003
Orchard Jenny, Garand Richard, Davis Zadie, Babbage Gavin, Sahota Surinder, Matutes Estella, Catovsky Daniel, Thomas Peter W, Avet-Loiseau Hervé, Oscier David
Abstract excerpt
We analyzed lymphocyte morphology, histology, immunophenotype, immunoglobulin heavy chain (IgVH) gene mutations, and clinical course in 80 unselected patients presenting with circulating t(11;14) lymphocytes. Of the 80 patients, 43 had peripheral lymphadenopathy (nodal group), and histology confirmed mantle cell lymphoma (MCL) in all. There were 37 patients with no lymphadenopathy (nonnodal group); 13 of 37 had...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
