Article
[Mantle cell lymphoma: Towards a personalized therapeutic strategy?].
Medicina clinica - 22 Jun 2015
Navarro Matilla Belén, García-Marco José A
Abstract excerpt
Mantle cell lymphoma (MCL) is a clinically heterogeneous non-Hodgkin lymphoma with an aggressive clinical behaviour and short survival in some cases and an indolent course in others. Advances in the biology and pathogenesis of MCL have unveiled several genes involved in deregulation of cell cycle checkpoints and the finding of subclonal populations with specific recurrent mutations (p53, ATM, NOTCH2) with an...
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