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Article

Absence of CD38 expression in mantle cell lymphoma correlates with distinct pathological and genetic features.

Human pathology - 1 Jun 2026

Abu Mehsen Sara, Monika Fnu, Sharma Shidhant, Idiaquez Dietrich Werner, Al-Othman Yazan, Tashkandi Hammad, Zhang Ling, Yan Mingfei

Abstract excerpt

Although CD38 is commonly expressed in mantle cell lymphoma (MCL), a subset of cases lacks CD38 expression, and the biological significance of CD38 negativity remains incompletely understood. In this study, we analyzed 188 MCL patients with available flow cytometry data and stratified cases into CD38-negative and CD38-positive groups based on median fluorescence intensity (MFI). CD38 expression was detected in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41850632
DOI: 10.1016/j.humpath.2026.106107

Genes

CD38
TP53
ATM
CD79B
CXCR4
KMT2D
NOTCH1
NOTCH2
NSD2
SOX11
TRAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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