Article
The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival.
Cancer research - 1 Dec 2003
Martínez Nerea, Camacho Francisca I, Algara Patrocinio, Rodríguez Antonia, Dopazo Ana, Ruíz-Ballesteros Elena, Martín Paloma, Martínez-Climent Jose A, García-Conde Javier, Menárguez Javier, Solano Fernando, Mollejo Manuela, Piris Miguel A
Abstract excerpt
Mantle cell lymphoma (MCL) is a prototypical neoplastic disease in which a common cytogenetic alteration, t11;14, leading to cyclin D1 overexpression, is associated with other changes that need to be considered in an explanation of the clinical, morphological, and molecular variability of this disease. Using a cDNA microarray (Oncochip-CNIO) containing clones for 6386 cancer-related genes, we have analyzed the...
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