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Article

Genetic markers associated with abstinence length in alcohol-dependent subjects treated with acamprosate.

Translational psychiatry - 7 Oct 2014

Karpyak V M, Biernacka J M, Geske J R, Jenkins G D, Cunningham J M, Rüegg J, Kononenko O, Leontovich A A, Abulseoud O A, Hall-Flavin D K, Loukianova L L, Schneekloth T D, Skime M K, Frank J, Nöthen M M, Rietschel M, Kiefer F, Mann K F, Weinshilboum R M, Frye M A, Choi D S

Abstract excerpt

Acamprosate supports abstinence in some alcohol-dependent subjects, yet predictors of response are unknown. To identify response biomarkers, we investigated associations of abstinence length with polymorphisms in candidate genes in glycine and glutamate neurotransmission pathways and genes previo...

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Identifiers

PMID: 25290263
DOI: 10.1038/tp.2014.103
PMCID: PMC4350512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25290263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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