Article
Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate.
The pharmacogenomics journal - 1 Oct 2011
Kiefer F, Witt S H, Frank J, Richter A, Treutlein J, Lemenager T, Nöthen M M, Cichon S, Batra A, Berner M, Wodarz N, Zimmermann U S, Spanagel R, Wiedemann K, Smolka M N, Heinz A, Rietschel M, Mann K
Abstract excerpt
In alcoholism, both relapse to alcohol drinking and treatment response are suggested to be genetically modulated. This study set out to determine whether the top 15 single nucleotide polymorphisms (SNPs) of a recent genome-wide association (GWA) and follow-up study of alcohol dependence are associated with relapse behavior and pharmacological treatment response in 374 alcohol-dependent subjects who underwent a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.