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Article

FLT3 expression and IL10 promoter polymorphism in acute myeloid leukemia with RUNX1-RUNX1T1.

Molecular biology reports - 1 Feb 2015

Kim Myungshin, Kim Jiyeon, Kim Jung Rok, Han Eunhee, Park Joonhong, Lim Jihyang, Kim Yonggoo, Han Kyungja, Kim Hee-Je, Min Woo-Sung, Cho Bin

Abstract excerpt

We investigated the correlation between FLT3 expression and IL10 gene promoter polymorphism in acute myeloid leukemia with RUNX1-RUNX1T1 and their clinical significance. FLT3 mRNA expression was measured by real-time quantitative PCR (qPCR) and immunohistochemical staining (IHC) on bone marrow (BM) leukemic cells. IL10 gene promoter polymorphisms including rs1800896 (G-1082A), rs1800871 (C-819T), and rs1800872...

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Topics

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Share to Core Binding Factor Alpha 2 Subunit
Share to fms-Like Tyrosine Kinase 3
Share to Gene Expression Regulation, Leukemic
Share to Interleukin-10
Share to Interleukin-1beta
Share to Oncogene Proteins, Fusion
Share to RUNX1 Translocation Partner 1 Protein
Share to Translocation, Genetic

Source

Identifiers

PMID: 25287662
DOI: 10.1007/s11033-014-3786-1

Genes

FLT3
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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