Article
The Drosophila Sp8 transcription factor Buttonhead prevents premature differentiation of intermediate neural progenitors.
eLife - 6 Oct 2014
Xie Yonggang, Li Xiaosu, Zhang Xian, Mei Shaolin, Li Hongyu, Urso Andreacarola, Zhu Sijun
Abstract excerpt
Intermediate neural progenitor cells (INPs) need to avoid differentiation and cell cycle exit while maintaining restricted developmental potential, but mechanisms preventing differentiation and cell cycle exit of INPs are not well understood. In this study, we report that the Drosophila homolog of mammalian Sp8 transcription factor Buttonhead (Btd) prevents premature differentiation and cell cycle exit of INPs in...
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