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Association between PGC-1alpha gene polymorphisms and type 2 diabetes risk: a case-control study of an Iranian population.

Canadian journal of diabetes - 1 Feb 2015

Shokouhi Shabnam, Haghani Karimeh, Borji Parveneh, Bakhtiyari Salar

Abstract excerpt

OBJECTIVE: The peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) gene could play a role in the onset of type 2 diabetes mellitus. The aim of this study was to explore the possible associations among polymorphisms Gly482Ser, Thr394Thr and Thr528Thr of the PGC-1alpha gene and the risk of type 2 diabetes in Kurdish-Iranians. METHODS: DNA specimens from all 173 type 2 diabetes subjects...

Topics

Adult
Aged
Case-Control Studies
Diabetes Mellitus, Type 2
Female
Genetic Association Studies
Genotype
Humans
Iran
Male
Middle Aged
Odds Ratio

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

Polymorphism, Genetic

Transcription Factors

Source

Identifiers

PMID: 25282005
DOI: 10.1016/j.jcjd.2014.05.003

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association between PGC-1alpha gene polymorphisms and type 2 diabetes risk: a case-control study of an Iranian population.PMID 25282005Read ↗

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A Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene is associated with type 2 diabetes in Caucasians.Semantic proximity Read ↗

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