Article
Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus.
Diabetologia - 1 Dec 2001
Ek J, Andersen G, Urhammer S A, Gaede P H, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O
Abstract excerpt
AIM/HYPOTHESIS: This study aimed to investigate if variability in the peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene is associated with Type II (non-insulin-dependent) diabetes mellitus. METHODS: The PGC-1 gene was examined in 53 Type II diabetic patients applying single strand conformational polymorphism analysis followed by nucleotide sequencing. Identified variants were genotyped...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.