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Article

Heme oxygenase-1 promoter polymorphisms and neonatal jaundice.

Neonatology - 1 Jan 2014

Kaplan Michael, Renbaum Paul, Hammerman Cathy, Vreman Hendrik J, Wong Ronald J, Stevenson David K

Abstract excerpt

BACKGROUND: Heme oxygenase (HO) is the initial, rate-limiting enzyme in the conversion of heme to bilirubin. Dinucleotide (GT)n repeat length in the promoter region of the encoding gene modulates transcription: shorter alleles, in contrast with longer allele counterparts, are associated with greater gene expression and should result in increased heme catabolism. OBJECTIVE: We compared the rates of heme catabolism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25277974
DOI: 10.1159/000365744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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