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Article

Association of HMOX1 gene promoter polymorphisms with hyperbilirubinemia in the early neonatal period.

Pediatrics international : official journal of the Japan Pediatric Society - 1 Aug 2015

Katayama Yoshinori, Yokota Tomoyuki, Zhao Hui, Wong Ronald J, Stevenson David K, Taniguchi-Ikeda Mariko, Nakamura Hajime, Iijima Kazumoto, Morioka Ichiro

Abstract excerpt

BACKGROUND: Heme oxygenase (HO) is the rate-limiting enzyme in the heme degradation pathway that produces bilirubin. The promoter region of human heme oxygenase-1 (HMOX1) contains a polymorphic (GT)n repeat that can regulate gene expression. Here, we investigated the association of (GT)n repeat length in the HMOX1 promoter region with neonatal hyperbilirubinemia in a population of Japanese term neonates. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25625535
DOI: 10.1111/ped.12591

Genes

HMOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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