Article
Marked hyperbilirubinemia associated with the heme oxygenase-1 gene promoter microsatellite polymorphism in a boy with autoimmune hemolytic anemia.
Pediatrics - 1 Mar 2007
Immenschuh Stephan, Shan Ying, Kroll Hartmut, Santoso Sentot, Wössmann Wilhelm, Bein Gregor, Bonkovsky Herbert L
Abstract excerpt
Mild hyperbilirubinemia is a clinical feature of hemolysis. Here we describe a boy with marked elevation of serum bilirubin values (maximum: 70 mg/dL) during an acute episode of autoimmune hemolytic anemia, which returned to within the reference range after clinical improvement. The boy was a homozygous carrier of short alleles of the heme oxygenase-1 (HO-1) gene GT dinucleotide-repeat promoter polymorphism,...
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