Article
First experimental evidence for the presence of a CRISPR toxin in sulfolobus.
Journal of molecular biology - 11 Nov 2014
He Fei, Chen Lanming, Peng Xu
Abstract excerpt
Clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated (cas) genes constitute the adaptive immune system in bacteria and archaea. Although the CRISPR-Cas systems have been hypothesized to encode potential toxins, no experimental data supporting the hypothesis are available in the literature. In this work, we provide the first experimental evidence for the presence of a toxin gene...
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