Article
Contribution of the nos-pdt operon to virulence phenotypes in methicillin-sensitive Staphylococcus aureus.
PloS one - 1 Jan 2014
Sapp April M, Mogen Austin B, Almand Erin A, Rivera Frances E, Shaw Lindsey N, Richardson Anthony R, Rice Kelly C
Abstract excerpt
Nitric oxide (NO) is emerging as an important regulator of bacterial stress resistance, biofilm development, and virulence. One potential source of endogenous NO production in the pathogen Staphylococcus aureus is its NO-synthase (saNOS) enzyme, encoded by the nos gene. Although a role for saNOS in oxidative stress resistance, antibiotic resistance, and virulence has been recently-described, insights into the...
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