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Article

Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development.

The Journal of biological chemistry - 1 Mar 2013

van Sorge Nina M, Beasley Federico C, Gusarov Ivan, Gonzalez David J, von Köckritz-Blickwede Maren, Anik Sabina, Borkowski Andrew W, Dorrestein Pieter C, Nudler Evgeny, Nizet Victor

Abstract excerpt

Staphylococcus aureus infections present an enormous global health concern complicated by an alarming increase in antibiotic resistance. S. aureus is among the few bacterial species that express nitric-oxide synthase (bNOS) and thus can catalyze NO production from L-arginine. Here we generate an...

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Identifiers

PMID: 23322784
DOI: 10.1074/jbc.M112.448738
PMCID: PMC3585076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23322784-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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