Article
AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Oct 2012
Sanderson Jennifer L, Gorski Jessica A, Gibson Emily S, Lam Philip, Freund Ronald K, Chick Wallace S, Dell'Acqua Mark L
Abstract excerpt
AMPA receptors (AMPARs) are tetrameric ion channels assembled from GluA1-GluA4 subunits that mediate the majority of fast excitatory synaptic transmission in the brain. In the hippocampus, most synaptic AMPARs are composed of GluA1/2 or GluA2/3 with the GluA2 subunit preventing Ca(2+) influx. How...
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