Article
Higher order oligomerization is required for H-NS family member MvaT to form gene-silencing nucleoprotein filament.
Nucleic acids research - 1 Oct 2012
Winardhi Ricksen S, Fu Wenbo, Castang Sandra, Li Yanan, Dove Simon L, Yan Jie
Abstract excerpt
MvaT from Pseudomonas aeruginosa is a member of the histone-like nucleoid structuring protein (H-NS) family of nucleoid-associated proteins widely spread among Gram-negative bacteria that functions to repress the expression of many genes. Recently, it was reported that H-NS from Escherichia coli can form rigid nucleoproteins filaments on DNA, which are important for their gene-silencing function. This raises a...
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