Article
The global regulator H-NS acts directly on the transpososome to promote Tn10 transposition.
Genes & development - 15 Sept 2005
Wardle Simon J, O'Carroll Michelle, Derbyshire Keith M, Haniford David B
Abstract excerpt
The histone-like nucleoid structuring (H-NS) protein is a global transcriptional regulator that is known to regulate stress response pathways and virulence genes in bacteria. It has also been implicated in the regulation of bacterial transposition systems, including Tn10. We demonstrate here that H-NS promotes Tn10 transposition by binding directly to the transposition complex (or transpososome). We present...
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