Article
Genetic polymorphism and prostate cancer aggressiveness: a case-only study of 1,536 GWAS and candidate SNPs in African-Americans and European-Americans.
The Prostate - 1 Jan 2013
Bensen Jeannette T, Xu Zongli, Smith Gary J, Mohler James L, Fontham Elizabeth T H, Taylor Jack A
Abstract excerpt
BACKGROUND: Genome-wide association studies have established a number of replicated single nucleotide polymorphisms (SNPs) for susceptibility to prostate cancer (CaP), but it is unclear whether these susceptibility SNPs are also associated with disease aggressiveness. This study evaluates whether such replication SNPs or other candidate SNPs are associated with CaP aggressiveness in African-American (AA) and...
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