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Article

Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort.

BMC medical genetics - 2 Oct 2014

Kedenko Lyudmyla, Lamina Claudia, Kedenko Igor, Kollerits Barbara, Kiesslich Tobias, Iglseder Bernhard, Kronenberg Florian, Paulweber Bernhard

Abstract excerpt

BACKGROUND: SIRT1 and FOXO1 interact with each other in multiple pathways regulating aging, metabolism and resistance to oxidative stress and control different pathways involved in atherosclerotic process. It is not known, if genetic polymorphisms (SNPs) at the SIRT1 and FOXO1 have an influence on carotid atherosclerosis. METHODS: Intima-media thickness (IMT) was measured on the common and internal carotid...

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Topics

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Share to Carotid Artery Diseases
Share to Carotid Intima-Media Thickness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Forkhead Box Protein O1

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Share to Genetic Association Studies

Share to Polymorphism, Single Nucleotide

Share to Sirtuin 1

Source

Open in PubMed Open full text

Identifiers

PMID: 25273948
DOI: 10.1186/s12881-014-0112-7
PMCID: PMC4411770

Genes

FOXO1
SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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