G protein-coupled receptors: abnormalities in signal transmission, disease states and pharmacotherapy.

Abstract excerpt

The aim of this review is to present the research results and draw new conclusions about the impact of alterations in the signal transmission through the G protein-coupled receptors (GPCRs) on the formation of diseases and drug therapy. GPCR family is the largest and the most diverse group of membrane receptors. They transmit signals into the cell by interaction with different ligands, which include, inter alia,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drug Therapy
• Share to Ligands
• Share to Molecular Targeted Therapy