Article
G protein-coupled receptors: dominant players in cell-cell communication.
International review of cytology - 1 Jan 2002
Bockaert Joël, Claeysen Sylvie, Bécamel Carine, Pinloche Sylvie, Dumuis Aline
Abstract excerpt
The G protein-coupled receptors (GPCRs) are the most numerous and the most diverse type of receptors (1-5% of the complete invertebrate and vertebrate genomes). They transduce messages as different as odorants, nucleotides, nucleosides, peptides, lipids, and proteins. There are at least eight families of GPCRs that show no sequence similarities and that use different domains to bind ligands and activate a similar...
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