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Article

Mycobacterium tuberculosis requires the ECF sigma factor SigE to arrest phagosome maturation.

PloS one - 1 Jan 2014

Casonato Stefano, Provvedi Roberta, Dainese Elisa, Palù Giorgio, Manganelli Riccardo

Abstract excerpt

SigE represents one of the best characterized alternative sigma factors of Mycobacterium tuberculosis, playing a major role in the response to several environmental stresses and essential for growth in macrophages and virulence. In previous work we demonstrated that a mutant of M. tuberculosis in which the sigE gene was disrupted by a cassette conferring hygromycin resistance is a promising vaccine candidate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25268826
DOI: 10.1371/journal.pone.0108893
PMCID: PMC4182583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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