Article
Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis.
Infection and immunity - 1 Mar 2004
Geiman Deborah E, Kaushal Deepak, Ko Chiew, Tyagi Sandeep, Manabe Yukari C, Schroeder Benjamin G, Fleischmann Robert D, Morrison Norman E, Converse Paul J, Chen Ping, Bishai William R
Abstract excerpt
The Mycobacterium tuberculosis alternate sigma factor, SigF, is expressed during stationary growth phase and under stress conditions in vitro. To better understand the function of SigF we studied the phenotype of the M. tuberculosis DeltasigF mutant in vivo during mouse infection, tested the muta...
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