Article
The Mycobacterium tuberculosis sigJ gene controls sensitivity of the bacterium to hydrogen peroxide.
FEMS microbiology letters - 15 Aug 2004
Hu Yanmin, Kendall Sharon, Stoker Neil G, Coates Anthony R M
Abstract excerpt
Sigma factors are important global regulators which control bacterial gene expression during growth and in response to stress. Previous work showed that mRNA of the sigJ gene was up-regulated in late stationary-phase and after rifampicin treatment. In order to verify the function of SigJ, we constructed a Mycobacterium tuberculosis mutant lacking the sigJ gene. In a microaerophilic stationary-phase model, the...
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